Table 8.
Effects of cool white fluorescent and blue-enriched LED daytime lighting on tissue DNA levels (mg/g tissue) in C3H, C57BL/6, and BALB/c mice.
| C3H |
C57BL/6 |
BALB/c |
||||||||||
| CWF |
bLAD |
CWF |
bLAD |
CWF |
bLAD |
|||||||
| Tissue | M | F | M | F | M | F | M | F | M | F | M | F |
| Liver | 2.91 ± 0.03 | 2.94 ± 0.09 | 3.02 ± 0.04a,b | 3.00 ± 0.07a,b | 2.95 ± 0.10c,d | 3.03 ± 0.06a | 2.87 ± 0.13 | 2.72 ± 0.11a-g | 2.91 ± 0.12h | 3.09 ± 0.13a,b,g-i | 2.80 ± 0.11c,d,f,j | 3.03 ± 0.08a,b,e,g-i,k |
| Fat | 1.13 ± 0.07 | 1.04 ± 0.02 | 1.25 ± 0.04a,b | 1.07 ± 0.03a-c | 1.28 ± 0.05a,b | 1.26 ± 0.01a,b,d | 1.12 ± 0.04b,c,e,f | 1.14 ± 0.02c,e,f | 1.16 ± 0.04c,d | 1.27 ± 0.01a,b,d,g-i | 1.04 ± 0.02a,c,e-i,j | 1.11 ± 0.03b,c,e,f,j |
| Muscle | 2.74 ± 0.11 | 2.53 ± 0.09a | 3.19 ± 0.10a,b | 2.97 ± 0.08a-c | 3.07 ± 0.1a,b,c | 3.03 ± 0.09a,b | 2.91 ± 0.10a,b,e | 2.70 ± 0.08b,c-e,g | 3.11 ± 0.12a,b,g,h | 2.90 ± 0.06a-c,h,i | 2.91 ± 0.09a,b,c,e,i | 2.82 ± 0.07c-f,i |
| Heart | 3.01 ± 0.09 | 2.96 ± 0.04 | 3.35 ± 0.10a,b | 3.08 ± 0.05b,c | 3.02 ± 0.03b-d | 3.03 ± 0.06 | 3.00 ± 0.10 | 3.023 ± 0.06c | 3.11 ± 0.07b | 3.10 ± 0.04b,c | 2.87 ± 0.12c,d,h,i,j | 3.06 ± 0.08b,c,k |
| Lung | 1.99 ± 0.04 | 1.98 ± 0.03 | 2.18 ± 0.05a,b | 2.08 ± 0.04a-c | 2.23 ± 0.06a,b,d | 2.18 ± 0.05a,b,d | 1.97 ± 0.03c-f | 2.57 ± 0.11a-c,e-g | 2.22 ± 0.04a,b,g | 2.22 ± 0.06a,b,d,g | 2.01 ± 0.05e,f,h,I,j | 2.12 ± 0.09b,c |
| Kidney | 2.76 ± 0.04 | 2.86 ± 0.03 | 2.97 ± 0.03a,b | 2.92 ± 0.04a-c | 3.10 ± 0.08a-c,d | 2.90 ± 0.04a,b,e | 2.92 ± 0.06a,e | 2.85 ± 0.05a,c | 3.20 ± 0.04a,b,d,h | 3.00 ± 0.06a-d,f,g-h | 3.06 ± 0.04a-c,d,f-i | 2.93 ± 0.07a,b,e,i-k |
| Gut | 3.09 ± 0.04 | 3.14 ± 0.03 | 3.35 ± 0.06a,b | 3.32 ± 0.04a-c | 3.21 ± 0.03a-c,d | 3.09 ± 0.08c,d,e | 3.01 ± 0.11b-e | 3.02 ± 0.04b-e | 3.37 ± 0.07a-h | 3.31 ± 0.05a,b,f,-h | 2.95 ± 0.08a,b,d-i,j | 3.09 ± 0.06c-e,I,j |
| Brain | 1.35 ± 0.04 | 1.95 ± 0.06a | 2.05 ± 0.08a,b | 2.13 ± 0.06a-c | 2.14 ± 0.05a,b | 1.93 ± 0.05a,c-e | 2.02 ± 0.08a,d,e,f | 1.83 ± 0.08a-f | 2.09 ± 0.05b,f,h | 2.05 ± 0.04a,f,h | 2.06 ± 0.08a,b,f,h | 1.90 ± 0.07a,c-e,i,k |
| Testes | 2.66 ± 0.03 | _ | 2.85 ± 0.02a | _ | 2.95 ± 0.03a,c | _ | 2.94 ± 0.09c,d | _ | 2.92 ± 0.05a,c | _ | 2.95 ± 0.04a,c | _ |
| Ovary | _ | 2.70 ± 0.06 | _ | 2.78 ± 0.05 | _ | 2.90 ± 0.03b,d | _ | 2.70 ± 0.04f | _ | 2.88 ± 0.03b,d,h | _ | 2.76 ± 0.10f,j |
Values represent means ± 1 SD (n = 30/group; that is, 30 males and 30 females in each lighting environment per strain).
P < 0.05 compared with value for C3H mice in male CWF control group.
P < 0.05 compared with value for C3H mice in female CWF control group.
P < 0.05 compared with value for C3H mice in male bLAD experimental group.
P < 0.05 compared with value for C3H mice in female bLAD experimental group.
P < 0.05 compared with value for C57BL/6 mice in male CWF control group.
P < 0.05 compared with value for C57BL/6 mice in female CWF control group.
P < 0.05 compared with value for C57BL/6 mice in male bLAD experimental group.
P < 0.05 compared with value for C57BL/6 mice in female bLAD experimental group.
P < 0.05 compared with value for BALB/c mice in male CWF control group.
P < 0.05 compared with value for BALB/c mice in female CWF control group.
P < 0.05 compared with value for BALB/c mice in male bLAD experimental group.