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. 2019 Oct;69(5):350–373. doi: 10.30802/AALAS-CM-19-000001

Table 8.

Effects of cool white fluorescent and blue-enriched LED daytime lighting on tissue DNA levels (mg/g tissue) in C3H, C57BL/6, and BALB/c mice.

C3H
C57BL/6
BALB/c
CWF
bLAD
CWF
bLAD
CWF
bLAD
Tissue M F M F M F M F M F M F
Liver 2.91 ± 0.03 2.94 ± 0.09 3.02 ± 0.04a,b 3.00 ± 0.07a,b 2.95 ± 0.10c,d 3.03 ± 0.06a 2.87 ± 0.13 2.72 ± 0.11a-g 2.91 ± 0.12h 3.09 ± 0.13a,b,g-i 2.80 ± 0.11c,d,f,j 3.03 ± 0.08a,b,e,g-i,k
Fat 1.13 ± 0.07 1.04 ± 0.02 1.25 ± 0.04a,b 1.07 ± 0.03a-c 1.28 ± 0.05a,b 1.26 ± 0.01a,b,d 1.12 ± 0.04b,c,e,f 1.14 ± 0.02c,e,f 1.16 ± 0.04c,d 1.27 ± 0.01a,b,d,g-i 1.04 ± 0.02a,c,e-i,j 1.11 ± 0.03b,c,e,f,j
Muscle 2.74 ± 0.11 2.53 ± 0.09a 3.19 ± 0.10a,b 2.97 ± 0.08a-c 3.07 ± 0.1a,b,c 3.03 ± 0.09a,b 2.91 ± 0.10a,b,e 2.70 ± 0.08b,c-e,g 3.11 ± 0.12a,b,g,h 2.90 ± 0.06a-c,h,i 2.91 ± 0.09a,b,c,e,i 2.82 ± 0.07c-f,i
Heart 3.01 ± 0.09 2.96 ± 0.04 3.35 ± 0.10a,b 3.08 ± 0.05b,c 3.02 ± 0.03b-d 3.03 ± 0.06 3.00 ± 0.10 3.023 ± 0.06c 3.11 ± 0.07b 3.10 ± 0.04b,c 2.87 ± 0.12c,d,h,i,j 3.06 ± 0.08b,c,k
Lung 1.99 ± 0.04 1.98 ± 0.03 2.18 ± 0.05a,b 2.08 ± 0.04a-c 2.23 ± 0.06a,b,d 2.18 ± 0.05a,b,d 1.97 ± 0.03c-f 2.57 ± 0.11a-c,e-g 2.22 ± 0.04a,b,g 2.22 ± 0.06a,b,d,g 2.01 ± 0.05e,f,h,I,j 2.12 ± 0.09b,c
Kidney 2.76 ± 0.04 2.86 ± 0.03 2.97 ± 0.03a,b 2.92 ± 0.04a-c 3.10 ± 0.08a-c,d 2.90 ± 0.04a,b,e 2.92 ± 0.06a,e 2.85 ± 0.05a,c 3.20 ± 0.04a,b,d,h 3.00 ± 0.06a-d,f,g-h 3.06 ± 0.04a-c,d,f-i 2.93 ± 0.07a,b,e,i-k
Gut 3.09 ± 0.04 3.14 ± 0.03 3.35 ± 0.06a,b 3.32 ± 0.04a-c 3.21 ± 0.03a-c,d 3.09 ± 0.08c,d,e 3.01 ± 0.11b-e 3.02 ± 0.04b-e 3.37 ± 0.07a-h 3.31 ± 0.05a,b,f,-h 2.95 ± 0.08a,b,d-i,j 3.09 ± 0.06c-e,I,j
Brain 1.35 ± 0.04 1.95 ± 0.06a 2.05 ± 0.08a,b 2.13 ± 0.06a-c 2.14 ± 0.05a,b 1.93 ± 0.05a,c-e 2.02 ± 0.08a,d,e,f 1.83 ± 0.08a-f 2.09 ± 0.05b,f,h 2.05 ± 0.04a,f,h 2.06 ± 0.08a,b,f,h 1.90 ± 0.07a,c-e,i,k
Testes 2.66 ± 0.03 _ 2.85 ± 0.02a _ 2.95 ± 0.03a,c _ 2.94 ± 0.09c,d _ 2.92 ± 0.05a,c _ 2.95 ± 0.04a,c _
Ovary _ 2.70 ± 0.06 _ 2.78 ± 0.05 _ 2.90 ± 0.03b,d _ 2.70 ± 0.04f _ 2.88 ± 0.03b,d,h _ 2.76 ± 0.10f,j

Values represent means ± 1 SD (n = 30/group; that is, 30 males and 30 females in each lighting environment per strain).

a

P < 0.05 compared with value for C3H mice in male CWF control group.

b

P < 0.05 compared with value for C3H mice in female CWF control group.

c

P < 0.05 compared with value for C3H mice in male bLAD experimental group.

d

P < 0.05 compared with value for C3H mice in female bLAD experimental group.

e

P < 0.05 compared with value for C57BL/6 mice in male CWF control group.

f

P < 0.05 compared with value for C57BL/6 mice in female CWF control group.

g

P < 0.05 compared with value for C57BL/6 mice in male bLAD experimental group.

h

P < 0.05 compared with value for C57BL/6 mice in female bLAD experimental group.

i

P < 0.05 compared with value for BALB/c mice in male CWF control group.

j

P < 0.05 compared with value for BALB/c mice in female CWF control group.

k

P < 0.05 compared with value for BALB/c mice in male bLAD experimental group.