Figure 6.

(A) Best docking solution for the interaction of compound 5 within the active site of TcCA. Histidine and important residues of the active site are highlighted in grey for carbon atoms, in red for oxygen atoms and in blue for nitrogen atoms. The zinc ion is represented as a non-bonded sphere in cyan. Colour code for compound 5: Carbon atoms in green, Nitrogen atoms in blue, sulphur atoms in yellow and oxygen atoms in red. (B) Schematic representation of the interactions between compound 5 and the active site of the TcCA model.