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. 2019 Sep 13;11(10):2927–2940. doi: 10.1093/gbe/evz198

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© The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5. — —A model for the generation and continued increase of EPSPS copy number. The initial event that led to EPSPS gene duplication was the insertion of two mobile elements both up- and downstream of the EPSPS gene (MGE). After unequal crossing over, gametes were produced with >1 EPSPS gene copy. Subsequently, a double stranded break occurred at the MGE boundary that was incorrectly repaired using a microhomology-mediated mechanism within the middle of the repeat region, generating a shorter copy of this repeat region (32.7-kb repeat).