Table 2.

CotB2 and its variants as well as the altered products.

variant	product	reference
wild-type	cyclooctat-9-en-7-ol (4)	[31]
N103A	3,7,12-dolabellatriene (6)	[36]
F107A	R-cembrene A (7)	[30]
F107Y	cyclooctat-1,7-diene (8)	[30]
F107L	cyclooctat-9-en-7-ol (4) 3,7-dolabelladiene-9-ol (9) cyclooctat-6-en-8-ol (10)	[30,36]
F149L	cyclooctat-7-en-3-ol (11)	[30]
F185A	cyclooctat-9-en-7-ol (4) cyclooctat-6-en-8-ol (10)	[36]
W186L	cyclooctat-9-en-7-ol (4) cembrane A (7) 3,7,18-dolabellatriene (12)	[36]
W186F	cyclooctat-9-en-7-ol (4) cyclooctat-7-en-3-ol (11) 3,7-dolabelladiene-9-ol (9) cyclooctat-6-en-8-ol (10)	[36]
W186H	cyclooctat-7-en-3-ol (11) 3,7,18-dolabellatriene (12)	[36,38]
W288G	3,7,18-dolabellatriene (12)	[38]