Table 1.
Mapping program | No. of correct alignments out of 269 known fusion transcriptsa | ||
---|---|---|---|
50 bp | 75 bp | 100 bp | |
GMAP | 59 | 28 | 3 |
SSAHA2 | 237 | 248 | 252 |
Bowtie2 | 242 | 245 | 248 |
BWA | 1 | 238 | 244 |
BLAT | 218 | 225 | 226 |
TopHat2 | 227 | 228 | 226 |
All alignment tools were run with default options.
RNA-Seq, RNA sequencing.
Two hundred sixty-nine known fusion transcripts were collected from TICdb and ChimerDB 2.0.