Table 1. Relevant quantities of influenza virus and parameters in multi-strain SIR model.
Symbol | Definition | Typical values for influenza | Range in simulations |
---|---|---|---|
Fraction of population infected with strain | |||
Population average susceptibility to strain | ∼0.5 | ||
Total prevalence | |||
Average total prevalence | 0.005 | ||
Cross-immunity range | [50, 200] | ||
Transmission rate | ∼0.5/day | 2 | |
Recovery rate | ∼0.2/day | 1 (sets unit of time) | |
Host birth/death rate | ∼0.01/year | 0 | |
Cross-immunity of strains , | |||
Coalescent time scale/sweep time | ∼2-6 years | ||
Time to most recent common ancestor | ∼2-10 years | ||
Fluctuations of | ∼2-6 years | ||
Selection coefficient | ∼0.03/week | [0.003, 0.05] | |
Beneficial mutation rate per genome | 10-3/week | [10-7,10-3] | |
Host population | 1010 | [106, 1012] |