Table I.

Comparison of reproductive changes seen in transgender men given T therapy and in our mouse model of postpubertal T therapy.

Reproductive effects of postpubertal T therapy	Transgender men with T therapy	Mouse model with T therapy
Acyclicity	✓a	✓
T in male range	✓b	✓
LH reduction	✓c	✓
Ovarian phenotype similar to polycystic ovary morphology	✓d	✓

Citations: ^a(Meyer et al., 1986; Grimstad et al., 2019), ^b(Hembree et al., 2017), ^c(Spinder et al., 1989; Wierckx et al., 2014), ^d(Futterweit and Deligdisch, 1986; Spinder et al., 1989). T, testosterone