Fig. 3. Gene conversion acts like weak selection to remove PRDM9 binding sites.
Strength of selection acting against PRDM9-A binding alleles for different populations in different bins of recombination rate. Bin 1 is for per-generation rates, r ∈ [0,1.45 × 10−9); bin 2 is r ∈ [1.45 × 10−9,2.78 × 10−9); bin 3 is r ∈ [2,78 × 10−9,5.25 × 10−9); bin 4 is r ∈ [5.25 × 10−9,1.19 × 10−8); and bin 5 is r ∈ [1.19 × 10−8, ∞). Bins were chosen such that approximately the same number of polymorphic PRDM9 binding sites falls within each bin. Selection is stronger at bins with higher recombination rates.