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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Cancer Res. 2019 Jul 4;79(17):4331–4338. doi: 10.1158/0008-5472.CAN-18-3394

Figure 3.

Figure 3

TMZ sensitizes MGMT-deficient tumors to ATR inhibitors in vitro. A, LN229 cells were treated with TMZ with or without ATR inhibitors ATRIN-119 [15 nM] or VX-970 [50 nM] and allowed to form colonies for 14 days. B, Hap1 cells were treated with TMZ with or without VX-970 [50 nM] for 72h and allowed to form colonies for 12 days. C, SW480 and SW620 cells were treated with TMZ with or without VX-970 [50 nM] for 72h and allowed to form colonies for 12 days. D, NCI-H446 cells were treated with TMZ with or without VX-970 [50 nM] for 72h and allowed to form colonies for 16 days.