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. Author manuscript; available in PMC: 2019 Dec 6.
Published in final edited form as: Biometrics. 2019 Apr 22;75(4):1253–1263. doi: 10.1111/biom.13067

Table 1.

Performance of our proposed estimation for ∆EB(t; t0) and the perturbation-resampling approach to obtain σ^EB(t,t0), in terms of bias, empirical standard error (ESE), average standard error (ASE) using σ^EB(t,t0), coverage of the 95% confidence intervals, and Type 1 error/power under three settings, setting (i) (null setting), setting (ii), and setting (iii); performance of σ^EB0 from Remark 1, where the standard error (SE) is derived under the null, and corresponding Type 1 error/power when this estimate is used for testing is also shown.


Setting (i)
t0 = 0.25 t0 = 0.50 t0 = 0.75
Bias −0.0001 −0.0002 −0.0001
ESE  0.0072  0.0108  0.0132
ASE  0.0076  0.0107  0.0134
Coverage  0.9570  0.9460  0.9540
Type 1 error  0.0360  0.0480  0.0410

SE derived under the null

σ^EB0/nB 0.0073 0.0106 0.0134
Type 1 error 0.0420 0.0520 0.0440

Setting (ii)

t0 = 0.25 t0 = 0.50 t0 = 0.75

Bias 0.0000 0.0002 0.0000
ESE 0.0065 0.0091 0.0114
ASE 0.0068 0.0095 0.0118
Coverage 0.9580 0.9600 0.9560
Power 0.3310 0.6230 0.7650

SE derived under the null

σ^EB0/nB
0.0064 0.0092 0.0117
Power 0.3850 0.6520 0.7760

Setting (iii)

t0 = 0.25 t0 = 0.50 t0 = 0.75

Bias 0.0001 0.0001 0.0000
ESE 0.0061 0.0086 0.0108
ASE 0.0066 0.0091 0.0112
Coverage 0.9550 0.9570 0.9540
Power 0.5170 0.8410 0.9420

SE derived under the null

σ^EB0/nB 0.0061 0.0088 0.0111
Power 0.5880 0.8590 0.9440