Table 2:

Quantification of major cell types in mucociliary-differentiated normal and COPD cultures

Cell type	Basal cells	Goblet cells	Club cells	Ciliated cells
Healthy non-smokers	25 ± 5.7	15 ± 4.1	8 ± 3.8	41 ± 8.4
COPD	38 ± 6.1*	25 ± 2.4*	9 ± 4.2	22 ± 6.4*

Mucociliary-differentiated airway epithelial cell cultures were fixed and probed with antibodies specific to basal, goblet, Club or ciliated cells. Different cell types were counted by immunofluorescence and expressed as number of cells per 100 cells. The data represent average ± S.D. calculated from cultures established from 6 healthy non-smokers and 6 COPD subjects (*p ≤ 0.05, unpaired t test).