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. 2019 Jun 30;12(1):2198. doi: 10.4022/jafib.2198

Table 2. Baseline characteristics of atrial fibrillation participants with and without a first-degree family history of the disease.

No First-Degree Family History of AF (n = 5136) First-Degree Family History of AF (n = 748) p-value
Basic demographics
Age, mean ± SD, years 57.0 ± 15.5 58.7 ± 12.8 0.0003
Sex 0.004
Male 2266 (60%) 390 (54%)
Female 1540 (40%) 336 (46%)
Country of birth <0.0001
USA 2801 (74%) 620 (85%)
Other 1002 (26%) 106 (15%)
Race/Ethnicity, n (%) 0.076
Black 64 (2%) 6 (0.83%)
White 3458 (91%) 684 (94.34%)
Asian 103 (3%) 15 (2.07%)
Native Hawaiian 4 (0.1%) 0 (0.00%)
American Indian 17 (0.5%) 0 (0.00%)
Other Don't know 61 (2%) 3 (0.08%) 5 (0.69%) 1 (0.1%)
Hispanic (ethnicity) 198 (5%) 22 (3%) 0.012
Medical history
Hypertension 2657 (52%) 376 (50%) 0.45
Diabetes 667 (13%) 77 (10%) 0.038
Coronary artery disease 1148 (22%) 126 (17%) 0.0006
Heart attack 662 (13%) 72 (10%) 0.011
Congestive heart failure 818 (16%) 103 (14%) 0.13
Stroke or TIA 583 (11%) 70 (9%) 0.10
Congenital heart disease 488 (10%) 47 (6%) 0.0041
Obstructive sleep apnea 1376 (27%) 208 (28%) 0.68
COPD 398 (8%) 60 (8%) 0.85
Asthma 617 (12%) 82 (11%) 0.36
Cardiac arrest 357 (7%) 40 (5%) 0.090
Implantable device 832 (16%) 105 (14%) 0.10
Smoking history
History of smoking regularly 1047 (46%) 324 (44%) 0.35
Current smoker 86 (4%) 23 (3%) 0.41
Alcohol Use
Did you drink alcoholic beverages in the past year? 1732 (77%) 573 (79%) 0.29
Did you drink alcohol more than once or twice in the past? 336 (65%) 98 (64%) 0.82
Drinks of wine/week 4.0 ± 24.9 3.6 ± 5.3 0.76
Drinks of beer/week 1.7 ± 8.1 1.5 ± 5.6 0.76
Drinks of hard liquor/week 1.4 ± 4.0 1.4 ± 5.0 0.77
During past 24 hours, how many drinks? 0.8 ± 2.4 1.0 ± 1.5 0.25
Approximately how many years ago did you stop drinking? 57.7 ± 291.4 32.5 ± 181.1 0.42
What is the usual number of drinks you consumed per week before you stopped? 12.4 ± 32.5 10.4 ± 19.2 0.55
Atrial fibrillation history
Symptoms when first diagnosed? 3517 (75%) 580 (78%) 0.20
Paroxysmal AF 2215 (48%) 365 (49%) 0.53
Hx of cardioversion 1448 (31%) 232 (31%) 0.96
Hx of AF ablation 1098 (24%) 208 (28%) 0.012
Atrial fibrillation symptoms (check all that apply)
Never have symptoms 610 (12%) 68 (0.09%) 0.026
Palpitations 3008 (59%) 474 (63%) 0.012
SOB 432 (8%) 84 (11%) 0.011
Difficulty exercising 103 (2%) 16 (2%) 0.81
Chest pain/pressure/discomfort 89 (2%) 25 (3%) 0.0029
Dizziness 93 (2%) 8 (1%) 0.15
Feeling generally tired 79 (2%) 11 (1%) 0.89
Feeling generally "off" your normal self 133 (3%) 41 (5%) <0.0001
Other 45 (1%) 12 (2%) 0.58
Don't know 610 (12%) 68 (9%) 0.026