Table 4.
Multivariate Cox Regression Analysis Of Clinicopathologic Characteristics With Overall Survival In Patients With CS
| Factor | Compared Subgroups | p | Relative Risk | 95% CI | |
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Age, years | <45/≥45 | 0.451 | 1.269 | 0.683 | 2.357 |
| Sex | Male/Female | 0.919 | 1.033 | 0.558 | 1.911 |
| Differentiation | I/II/III | 0.001 | 2.581 | 1.491 | 4.467 |
| Tumor size | <5 cm/≥5 cm | 0.147 | 0.519 | 0.214 | 1.258 |
| Metastasis | No/Yes | 0.029 | 6.640 | 1.216 | 36.247 |
| Invasion | No/Yes | 0.026 | 3.274 | 1.150 | 9.324 |
| AJCC stage | I/II/III/Ⅳ | 0.008 | 3.414 | 1.372 | 8.494 |
| Enneking stage | I/II/III | 0.009 | 3.418 | 1.358 | 8.603 |
| EAAT1 | –/+ | 0.005 | 2.912 | 1.369 | 6.194 |
| DHFR | –/+ | 0.020 | 2.732 | 1.174 | 6.358 |
| Fetuin-A | –/+ | 0.029 | 2.241 | 1.087 | 4.619 |
Abbreviations: CS, chondrosarcoma; EAAT1, excitatory amino acid transporter 1; DHFR, dihydrofolate reductase; N, number; AJCC, American Joint Committee on Cancer.