FIG 5.

Effects of intravitreous injection of phage ΦEF24C-P2 or VAN on the clinical signs of VRE2-induced endophthalmitis in mice. (A to C) The right eye was injected intravitreously with 1 × 10⁴ E. faecalis strain VRE2 cells. Six hours after infection, vehicle (A), ΦEF24C-P2 (1 × 10⁸ PFU) (B), or VAN (1 μg) (C) was administered intravitreously to the same eye. Representative photographs of the right eye at 24 h after VRE2 injection are shown. (D) Clinical score at 24 h after VRE2 injection for the treated mice. Data are means ± SEM for 14 eyes in each group. *, P < 0.05; **, P < 0.01 (Tukey-Kramer test) versus vehicle-treated eyes.