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Susceptibility and resistance of T. rubrum strain TIMM20092, and two TruMDR3 mutants, ΔTruMDR3-33 and ΔTruMDR3-45, to voriconazole (VRC) and itraconazole (ITC). (A) Serial dilution drug susceptibility assays to VRC and ITC. T. rubrum spores were spotted at different dilutions on SDA plates, as described in Materials and Methods. The plates were incubated at 30°C for 7 days. (B) Etest strips laced with VRC and ITC were placed on fungal lawns (106 CFU) prepared on SDA plates.
