FIG 7.

(A) Intron-exon structures of T. rubrum and A. fumigatus genes encoding ABC transporters. Green arrowheads indicate introns in ortholog positions. Red arrowheads indicate introns in other positions showing that the intron-exon structures of genes encoding T. rubrum azole ABC transporters and those of the closest homologs in A. fumigatus, are generally different. Refer to Table S3 for the amino acid positions in the transporter sequence, which correspond to the intron positions in the coding genes. (B) Comparison of the protein sequences encoded by the conserved intron region in TruMDR2 and A. fumigatus mdr1, and comparison of the protein sequences encoded by the two conserved intron regions in TruMDR1 and A. fumigatus abcA_2. The amino acid sequence coded by the 3′ extremity of the left exon is in red, and the amino acid sequence encoded by the 5′ extremity of the right exon is in black.