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. 2019 Oct 17;6:329. doi: 10.3389/fvets.2019.00329

Table 10.

Medically important antimicrobial use (all routes) by indication and class/type of antimicrobial drug (AMD)a, organized by category of importance to human medicineb, and expressed in number of animal daily doses (nADD).

Placement cohort (PC)c
1 2 3 4 Total
CATTLE AT RISK, NO.
717,176 670,066 648,916 578,924 2,615,082
CATTLE EXPOSED TO AMD PARENTERALLY, NO. (% OF CATTLE AT RISK IN PC)
537,599 (75) 498,618 (74) 457,940 (71) 416,668 (72) 1,910,825 (73)
CATTLE EXPOSED TO AMD IN FEED, NO. (% OF CATTLE AT RISK IN PC)
694,890 (97) 655,100 (98) 624,899 (96) 552,427 (95) 2,527,316 (97)
nadd, NO. (NO./100,000 CATTLE AT RISK)
I FQid 17,512 (2,442) 10,197 (1,522) 8,356 (1,288) 8,382 (1,448) 44,447 (1,700)
CEPHid 65,512 (9,135) 53,934 (8,049) 47,881 (7,379) 53,366 (9,218) 220,693 (8,439)
II MACid 587,157 (81,871) 505,405 (75,426) 539,728 (83,174) 489,167 (84,496) 2,121,457 (81,124)
MACif 524,514 (73,136) 492,342 (73,477) 462,974 (71,346) 423,624 (73,174) 1,903,454 (72,788)
PENid 687 (96) 492 (73) 415 (64) 55 (9) 1,649 (63)
TMSid 30,402 (4,239) 28,785 (4,296) 27,852 (4,292) 28,712 (4,960) 115,751 (4,426)
III TETid 942,109 (131,364) 857,577 (127,984) 688,886 (106,160) 584,480 (100,960) 3,073,052 (117,513)
TETif 7,776,118 (1,084,269) 7,047,227 (1,051,721) 6,642,928 (1,023,696) 5,320,871 (919,097) 26,787,144 (1,024,333)
PHENid 36,334 (5,066) 75,732 (11,302) 68,938 (10,624) 60,528 (10,455) 241,532 (9,236)
SULFid 497 (69) 396 (59) 245 (38) 279 (48) 1,417 (54)
TOTAL 9,980,842 (1,391,686) 9,072,087 (1,353,909) 8,488,203 (1,308,059) 6,969,464 (1,203,865) 34,510,596 (1,319,676)

Where number of cattle are presented, the number of cattle is presented to the left the cell with the % of cattle this number represents in the placement cohort in parentheses to the right of the cell. Where nADD are presented, the nADD is presented in the left part of the cell and the nADD/100,000 cattle is presented in the right part of the cell in parentheses.

a

FQ, fluoroquinolones; CEPH, 3rd generation cephalosporins; MAC, macrolides; PEN, penicillin; TMS, trimethoprim-sulfamethoxazole; TET, tetracyclines; PHEN, phenicols; SULF, sulfonamides. The superscript “id” indicates individually dosed and the superscript “if” indicates in feed.

b

Roman numerals I to III designate category of importance to human medicine as designated by the Canadian Veterinary Drugs Directorate.

c

Placement cohort comprised of cattle placed in the feedlot between 1 November and 31 October of consecutive years.