Table 4.
Individually dosed antimicrobial use by indicationa,b and class of antimicrobial drug (AMD)c, organized by category of importance to human medicined and expressed in number of animal daily doses (nADD).
| Indication | ||||||||
|---|---|---|---|---|---|---|---|---|
| ARD | UF/BRD | Lameness | Other | Implant | Total | |||
|
AMD
Class |
Metaphylaxis | Treatment | ||||||
| nADD No. (% of use of specific AMD class, % of use for specified indication) | ||||||||
| I | FQ | 3 (0.01, 0.01) | 0 (0, 0) | 44,192 (99.4, 7.9) | 71 (0.2, 0.03) | 181 (0.4, 0.1) | 0 (0, 0) | 44,447 |
| CEPH | 33,075 (15.0, 98.7) | 0 (0, 0) | 51,498 (23.3, 9.2) | 99,515 (45.1, 44.3) | 36,604 (16.6, 24.3) | 0 (0, 0) | 220,692 | |
| II | MAC | 85 (0.004, 0.25) | 1,975,173 (93.0, 40.7) | 143,019 (6.7, 25.6) | 602 (0.03, 0.3) | 2,579 (0.1, 1.7) | 3,061 (0.1, 100) | 2,124,519 |
| PEN | 3 (0.2, 0.01) | 0 (0, 0) | 13 (0.8, 0.002) | 1,347 (81.7, 0.6) | 286 (17.3, 0.2) | 0 (0, 0) | 1,649 | |
| TMS | 214 (0.2, 0.6) | 0 (0, 0) | 659 (0.6, 0.1) | 72,733 (62.8, 32.4) | 42,146 (36.4, 28.0) | 0 (0, 0) | 115,752 | |
| III | TET | 64 (0.002, 0.2) | 2,876,561 (93.6, 59.3) | 81,634 (2.7, 14.6) | 49,860 (1.6, 22.2) | 64,933 (2.1, 43.2) | 0 (0, 0) | 3,073,052 |
| PHEN | 74 (0.03, 0.2) | 584 (0.2, 0.01) | 238,256 (98.6, 42.6) | 360 (0.1, 0.2) | 2,258 (0.9, 1.5) | 0 (0, 0) | 241,532 | |
| SULF | 0 (0, 0) | 0 (0, 0) | 20 (1.4, 0.003) | 8 (0.6, 0.004) | 1,389 (98.0, 0.9) | 0 (0, 0) | 1,417 | |
| ALL | 33,518 | 4,852,318 | 559,291 | 224,496 | 150,376 | 3,061 | 5,823,060 | |
The nADD is presented on the left side of the cell. In parentheses on the right side of the cell, the % of use of the specific AMD class is first presented, then the % of use for specified indication presented separated by a comma. Percentages of use may not add to 100% due to rounding. Darkening green color indicates increasing nADD.
ARD, acute respiratory disease; UF/BRD, undifferentiated fever/bovine respiratory disease; Other, neurologic, metabolic, ocular, or other indications; Implant, antimicrobial associated with implantation of hormone.
Metaphylaxis, group administration of an antimicrobial to a population at risk for disease before overt clinical disease is apparent in the entire group; Treatment, administration of an antimicrobial to an individual animal diagnosed with clinical disease.
FQ, fluoroquinolones; CEPH, 3rd generation cephalosporins; MAC, macrolides; PEN, penicillins; TMS, trimethoprim-sulfamethoxazole; TET, tetracyclines; PHEN, phenicols; SULF, sulfonamides.
Roman numerals I to III signify categories of importance to human medicine as designated by the Canadian Veterinary Drugs Directorate.