Table 6.
Output of univariate regression analysis for estimates of relative risk of exposure to specific antimicrobial drugs (AMD) for indications of metaphylaxisa or treatmentb of bovine respiratory disease (BRD) in cattle classified as high risk (HR) for developing BRD and cattle classified as low risk (LR) for developing BRD.
| AMD | Indication | Regression coefficient | p value | Relative risk estimate | 95% confidence interval |
|---|---|---|---|---|---|
| Any | BRD (Metaphylaxis) | 0.49 | <0.0001 | 1.63 | 1.629–1.634 |
| BRD (Treatment) | 1.40 | <0.0001 | 4.07 | 4.025–4.114 | |
| Macrolide | BRD (Metaphylaxis) | 4.62 | <0.0001 | 101.55 | 98.976–104.199 |
| BRD (Treatment) | −0.16 | <0.0001 | 0.85 | 0.838–0.867 | |
| Tetracycline | BRD (Metaphylaxis) | −1.04 | <0.0001 | 0.35 | 0.352–0.354 |
| BRD (Treatment) | 0.08 | <0.0001 | 1.08 | 1.057–1.010 | |
| Phenicol | BRD (Metaphylaxis) | −0.26 | 0.07 | 0.77 | 0.583–1.023 |
| BRD (Treatment) | 0.84 | <0.0001 | 2.31 | 2.273–2.348 |
a
Metaphylaxis is the group administration of an antimicrobial to a population at risk for disease before overt clinical disease is apparent in the entire group.
b
Treatment is the administration of an antimicrobial to an individual animal diagnosed with clinical disease.