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. 2019 Oct 17;9:356. doi: 10.3389/fcimb.2019.00356

Figure 5.

Figure 5

Inactivation of lrp increased the cytotoxic effects of R20291 and 6301erm. Supernatants of R20291 and derivatives (A,B) and 630(Δ)erm and derivatives (C,D) from overnight cultured in TY medium were added to cultured cells and cytotoxicity was detected after 24 h. Caco-2 cells were used to determine the cytotoxicity of toxin A, while Vero cells were used to determine the cytotoxicity of toxin B. Statistical significance was set as follows: **p < 0.01; ****p < 0.0001). Data are represented as the mean ± standard error of the mean of three independent experiments.