Table 1.

Conservancy analysis of high-risk HPV L1 protein.

Protein Regions	Sequence and degree of conservancy
8–22 (Type 16)	EATVYLPPVPVSKVV
	16	18	31	33	35	39	45	51	52	56	58	59	68
	100.00%	60.00%	100.0%	100.0%	93.33%	60.00%	60.00%	60.00%	100.0%	80.00%	100.0%	60.00%	60.00%
8–22 (Type 18)	DNTVYLPPPSVARVV
	16	18	31	33	35	39	45	51	52	56	58	59	68
	80.00%	100.0%	76.67%	76.67%	76.67%	90.00%	86.67%	83.33%	83.33%	73.33%	83.33%	83.33%	86.67%
95–132 (Type 16)	TQRLVWACVGVEVGRGQPLGVGISGHPLLNKLDDTENA
	16	18	31	33	35	39	45	51	52	56	58	59	68
	100.00%	81.58%	92.11%	86.84%	92.11%	89.47%	81.58%	84.21%	84.21%	76.32%	81.58%	86.84%	81.58%
95–132 (Type 18)	TQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESS
	16	18	31	33	35	39	45	51	52	56	58	59	68
	81.58%	100.0%	78.95%	78.95%	81.58%	81.58%	89.47%	78.95%	81.58%	76.32%	81.58%	89.47%	89.47%
307–342 (Type 16)	FNKPYWLQRAQGHNNGICWGNQLFVTVVDTTRSTNM
	16	18	31	33	35	39	45	51	52	56	58	59	68
	100.00%	86.11%	97.22%	97.22%	97.22%	86.11%	88.89%	86.11%	100.0%	100.0%	100.0%	83.11%	86.11%
307–342 (Type 18)	FNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNL
	16	18	31	33	35	39	45	51	52	56	58	59	68
	86.11%	100.0%	83.33%	83.33%	86.11%	91.67%	97.22%	86.11%	86.11%	86.11%	86.11%	91.67%	91.67%
398–430 (Type 16)	ILEDWNFGLQPPPGGTLEDTYRFVTSQAIACQK
	16	18	31	33	35	39	45	51	52	56	58	59	68
	100.00%	71.43%	85.71%	78.57%	89.29%	53.57%	67.86%	64.29%	78.57%	60.71%	78.57%	71.43%	60.71%
399–431 (Type 18)	ILEDWNFGVPPPPTTSLVDTYRFVQSVAITCQK
	16	18	31	33	35	39	45	51	52	56	58	59	68
	71.43%	100.0%	71.43%	71.43%	67.86%	67.86%	96.43%	60.71%	71.43%	60.71%	71.43%	89.29%	75.00%
449–473 (Type 16)	VNLKEKFSADLDQFPLGRKFLLQAG
	16	18	31	33	35	39	45	51	52	56	58	59	68
	100.00%	84.00%	100.0%	96.00%	96.00%	80.00%	84.00%	80.00%	96.00%	76.00%	96.00%	88.00%	88.00%
450–474 (Type 18)	VDLKEKFSLDLDQYPLGRKFLVQAG
	16	18	31	33	35	39	45	51	52	56	58	59	68
	84.00%	100.0%	84.00%	88.00%	88.00%	80.00%	96.43%	80.00%	88.00%	88.00%	80.00%	80.00%	84.00%