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. 2019 Oct 23;9:15225. doi: 10.1038/s41598-019-51679-8

Table 2.

Conservancy analysis of high-risk HPV L2 protein.

Protein Regions Sequence and degree of conservancy
11–41 (Type 16) KRASATQLYKTCKQAGTCPPDIIPKVEGKTI
16 18 31 33 35 39 45 51 52 56 58 59 68
100.00% 80.00% 76.67% 83.33% 86.67% 76.67% 80.00% 76.67% 83.33% 73.33% 73.33% 73.33% 73.33%
10–40 (Type 18) KRASVTDLYKTCKQSGTCPPDVVPKVEGTTL
16 18 31 33 35 39 45 51 52 56 58 59 68
80.00% 100.0% 76.67% 76.67% 76.67% 90.00% 86.67% 83.33% 83.33% 73.33% 83.33% 83.33% 86.67%
96–120 (Type 16) DPVGPSDPSIVSLVEETSFIDAGAP
16 18 31 33 35 39 45 51 52 56 58 59 68
100.00% 60.0% 76.00% 80.00% 76.00% 64.00% 64.00% 48.00% 64.00% 64.00% 80.00% 68.00% 60.00%
94–118 (Type 18) EPVGPTDPSIVTLIEDSSVVTSGAP
16 18 31 33 35 39 45 51 52 56 58 59 68
60.00% 100.0% 64.0% 56.00% 52.0% 76.00% 92.00% 52.00% 56.00% 76.00% 60.00% 92.00% 80.00%
54–76 (Type 16) FFGGLGIGTGSGTGGRTGYIPLG
16 18 31 33 35 39 45 51 52 56 58 59 68
100.00% 95.65% 86.96% 86.96% 86.67% 91.30% 86.96% 91.30% 78.26% 78.26% 95.65% 95.65% 91.30%
53–75 (Type 18) FLGGLGIGTGSGTGGRTGYIPLG
16 18 31 33 35 39 45 51 52 56 58 59 68
95.65% 100.0% 82.61% 82.61% 82.61% 95.65% 91.30% 95.65% 73.91% 73.91% 91.30% 100.0% 67.86%
278–305 (Type 16) APDPDFLDIVALHRPALTSRRTGIRYSR
16 18 31 33 35 39 45 51 52 56 58 59 68
100.00% 67.86% 85.71% 78.57% 82.14% 78.57% 64.29% 78.57% 82.14% 75.00% 89.29% 75.00% 82.14%
271–298 (Type 18) VPDSDFMDIIRLHRPALTSRRGTVRFSR
16 18 31 33 35 39 45 51 52 56 58 59 68
67.86% 100.0% 78.57% 78.57% 78.57% 82.14% 96.43% 85.71% 85.71% 71.43% 78.57% 89.29% 85.71%