Table 8.
Proteasomal cleavage and TAP transport efficiency scores of MHC-I predicted epitopes.
| Protein Name | Position | Epitope Sequence | Proteasomal C terminal cleavage Score* | TAP transport efficiency Score** | Epitope identification Score*** |
|---|---|---|---|---|---|
| L1 | 12–21 (Type 16) | YLPPVPVSKV | 1.0473 | 0.9771 | 1.3162 |
| 12–21 (Type 18) | YLPPPSVARV | 0.9753 | 0.8581 | 0.9656 | |
| 114–125 (Type 16) | GVGISGHPLLNK | 0.8023 | 0.6695 | 0.7094 | |
| 104–115 (Type 18) | GVEIGRGQPLGV | 0.5253 | 0.9200 | 0.7017 | |
| 114–125 (Type 18) | GVGLSGHPFYNK | 0.3726 | 0.9360 | 0.6484 | |
| 411–421 (Type 16) | GGTLEDTYRFV | 0.5795 | 0.9599 | 0.8396 | |
| 414–425 (Type 18) | PTTSLVDTYRFV | 0.5992 | 0.9267 | 0.7579 | |
| 460–470 (Type 16) | DQFPLGRKFLL | 0.9879 | 0.9810 | 1.2046 | |
| 461–471 (Type 18) | DQYPLGRKFLV | 0.9358 | 0.9606 | 1.0779 | |
| L2 | 11–20 (Type 16) | KRASATQLYK | 1.3081 | 0.9773 | 1.6173 |
| 11–20 (Type 18) | KRASVTDLYK | 1.1145 | 0.9726 | 1.4230 | |
| 60–71 (Type 18) | GTGSGTGGRTGY | 0.4471 | 0.4000 | 0.5630 | |
| 280–291 (Type 16) | DPDFLDIVALHR | 0.8251 | 0.9405 | 1.0209 | |
| 293–303 (Type 16) | ALTSRRTGIRY | 0.6667 | 0.9280 | 0.8580 | |
| 273–284 (Type 18) | DSDFMDIIRLHR | 0.6514 | 0.9917 | 0.8881 | |
| 286–296 (Type 18) | ALTSRRGTVRF | 0.6545 | 0.8565 | 0.7305 |
*Higher rates show better quality of proteasomal cleavage, **Higher rates show better quality of tap transport efficiency, *** Higher rates show better quality of epitope identification.