Table 3.
Effects of pH on PS, PI, EE, and DL of NLCs.
| Formulation | pH | PS (nm) | PI | EE (%) | DL (%) |
|---|---|---|---|---|---|
| A1 | Water | 176 ± 2 | 0.19 ± 0.01 | 40.5 ± 7.7 | 3.89 ± 0.71 |
| A2 | 2 | 187 ± 1 | 0.22 ± 0.01 | 31.9 ± 3.3 | 3.09 ± 0.31 |
| A3 | 4 | 297 ± 13 | 0.30 ± 0.00 | 40.1 ± 2.3 | 3.86 ± 0.21 |
| A4 | 6 | 230 ± 1 | 0.29 ± 0.01 | 47.8 ± 5.4 | 4.56 ± 0.49 |
| A5 | 7.4 | 249 ± 3 | 0.33 ± 0.02 | 93.1 ± 0.3 | 8.52 ± 0.02 |
| A6 | 8 | 406 ± 4 | 0.58 ± 0.02 | 94.3 ± 1.0 | 8.62 ± 0.08 |
| A7 | 10 | 323 ± 6 | 0.59 ± 0.05 | 94.3 ± 0.8 | 8.62 ± 0.07 |
| A8 | 12 | 390 ± 13 | 0.63 ± 0.06 | 94.1 ± 1.6 | 8.60 ± 0.13 |
Composition of all the formulations was of tristearin: Phosal® 53MCT: OSH (60:40:10, w/w).