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. 2019 Sep 26;7(20):17237–17251. doi: 10.1021/acssuschemeng.9b03931

Figure 7.

Figure 7

Yield of rufinamide precursor in scale-up kinetic study of Huisgen cycloaddition: (a) Operating with 1.5 molar excess ratio of MOA. (b) Comparative results with different molar excess ratios at 160 and 175 °C.