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. 2019 Aug 28;29:182–196. doi: 10.1016/j.molmet.2019.08.016

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Partial deletion of Prok2 in the MOB deregulates food intake microstructure. Mice injected in the MOB with the scrambled-shRNA or Prok2-shRNA were placed in calorimetric cages (TSE system, Germany) 3 weeks postsurgery. The food intake pattern including number of bouts (A), number of meals (B), number of bouts per meal (C), food intake per bout (D), and per meal (E), as well as meal duration (F) were assessed. Values represent mean with SEM (n = 6/group), *, P < 0.05, **, P < 0.01 and ***, P < 0.001 vs scrambled-shRNA, using a two-way ANOVA followed by Bonferroni post hoc test.