Fig. 7.

Metabolic pathways associated with mitochondrial bioenergetics in vehicle control and Dox treated samples. Bubble plot showing metabolic pathways associated with mitochondrial bioenergetics before and after Dox Treatment. Pathway analysis was completed using mummichog on each bioenergetic parameter independently. The size and color of the bubbles represents the pathway significance level based on -Log₁₀P. Metabolic pathway analysis was performed using metabolic features associated with bioenergetics at |r|>0.6 and p < 0.05 using mummichog. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)