Table 2.
Relationships between bioenergetic parameters in the individual platelet samples prior to Dox treatment and the Dox metabolites.
| Correlations | ||||||
|---|---|---|---|---|---|---|
| Basal | AL | PL | Max | Res Cap | NonMito | |
| Dox | 0.6504 | 0.698 | −0.0738 | 0.0518 | −0.6783 | 0.2246 |
| Doxorubicinone | 0.5413 | 0.5686 | −0.3219 | 0.3002 | −0.2234 | 0.2219 |
|
| ||||||
| Correlation Probability | ||||||
| Basal |
AL |
PL |
Max |
Res Cap |
NonMito |
|
| Dox | 0.022 | 0.0116 | 0.8197 | 0.873 | 0.0153 | 0.4828 |
| Doxorubicinone | 0.0692 | 0.0537 | 0.3076 | 0.3431 | 0.4851 | 0.4881 |
Table 2 demonstrates the relationship between bioenergetic parameters and the unchanged Dox parent compound or Dox metabolites, such as doxorubicinone. The Pearson correlation coefficients were calculated using the JMP statistical program. * indicates p ≤ 0.05.