Fig. 8.

Enhanced median lifespan in G6PD-deficient mice. Untreated mice were monitored throughout their lifetime and times and apparent causes for death were recorded. Differences in survival were assessed by the log rank Mantel-Cox test. The number of mice for each genotype is shown in parentheses beside the respective survival curve. The median lifespans of homozygous female and hemizygous male G6PD-deficient mice were indistinguishable, and greater than those for either heterozygous G6PD-deficient females (+/def) (p < 0.01) or G6PD-normal wild-type males (def/y) or females (+/+) (p < 0.01).