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. 2019 Nov;371(2):260–267. doi: 10.1124/jpet.119.261529

Fig. 1.

Fig. 1.

Effects of NHBA on 10% ethanol drinking in C57BL/6J mice. (A) Experimental scheme. (B) The ratio of mice showing high ethanol drinking behavior. (C) Ethanol preference and (D) ethanol consumption during 10% ethanol drinking (n = 23/group). (E) Total distance traveled for 30 minutes in mice treated with NHBA (0.03, 0.1, 0.3 mg/kg; i.p.):-n = 7/VEH group, n = 5/NHBA groups. (F) Ethanol preference, (G) consumption, and (H) total liquid consumption in mice treated with NHBA 0.1 mg/kg (i.p.) for 3-hour drinking: n = 7/VEH group, n = 6/NHBA group. Data represented as mean ± S.E.M. *P < 0.05, (C and D) comparing water group, and (E–H) comparing vehicle treatment group. (C and D) Two-way repeated measures ANOVA followed by Bonferroni’s multiple comparisons test, (E) one-way ANOVA followed by Bonferroni’s multiple comparisons test, and (F–H) unpaired Student’s t test.