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. 2019 Oct 11;4(17):17438–17446. doi: 10.1021/acsomega.9b02236

Table 2. Effects of Dietary Supplementation of Resveratrol and Curcumin on Intestinal Antioxidant Capacity of Weaned Pigletsa,b,c.

items CON ANT HRC LRC RES CUR
Jejunum
GSH (nmol/mg prot) 1.96 ± 0.02c 2.48 ± 0.04a 2.62 ± 0.05a 2.17 ± 0.06b 2.24 ± 0.05b 2.10 ± 0.03bc
GSSG (nmol/mg prot) 0.17 ± 0.01a 0.16 ± 0.01a 0.13 ± 0.01b 0.15 ± 0.01ab 0.13 ± 0.01b 0.13 ± 0.01b
GSH/GSSG 12.03 ± 0.31c 14.67 ± 0.26bc 19.79 ± 1.01a 14.79 ± 0.89bc 16.79 ± 0.76b 15.73 ± 0.43b
GSH-PX (U/mg prot) 33.85 ± 1.06 36.05 ± 1.34 37.85 ± 0.47 34.50 ± 1.68 34.37 ± 2.61 35.90 ± 1.08
MDA (nmol/mg prot) 0.66 ± 0.05a 0.55 ± 0.02b 0.52 ± 0.03b 0.57 ± 0.02ab 0.62 ± 0.02ab 0.54 ± 0.03b
SOD (U/mg prot) 142.08 ± 12.08b 162.15 ± 10.71ab 170.96 ± 8.93a 144.26 ± 5.77b 170.88 ± 4.00a 154.44 ± 4.46ab
T-AOC (U/mg prot) 2.13 ± 0.09ab 2.31 ± 0.06b 2.59 ± 0.15a 2.44 ± 0.04ab 2.44 ± 0.04ab 2.45 ± 0.08ab
Ileum
GSH (nmol/mg prot) 1.93 ± 0.06b 2.32 ± 0.08a 2.28 ± 0.08ab 2.46 ± 0.14a 2.36 ± 0.03a 2.26 ± 0.06ab
GSSG (nmol/mg prot) 0.16 ± 0.01a 0.13 ± 0.01bc 0.13 ± 0.02bc 0.13 ± 0.01b 0.11 ± 0.01c 0.12 ± 0.01bc
GSH/GSSG 11.86 ± 0.33c 13.77 ± 0.48bc 17.08 ± 0.74ab 16.84 ± 1.48ab 17.67 ± 0.71a 16.93 ± 0.51ab
GSH-PX (U/mg prot) 30.91 ± 1.90 34.72 ± 1.18 36.32 ± 1.46 34.65 ± 1.07 36.38 ± 1.03 34.20 ± 1.60
MDA (nmol/mg prot) 0.68 ± 0.02a 0.60 ± 0.05b 0.53 ± 0.02b 0.54 ± 0.02b 0.62 ± 0.02b 0.56 ± 0.03b
SOD (U/mg prot) 137.56 ± 6.70 150.43 ± 4.92 168.30 ± 6.53 145.43 ± 8.34 161.88 ± 4.68 160.52 ± 14.10
T-AOC (U/mg prot) 2.02 ± 0.07b 2.50 ± 0.05a 2.48 ± 0.15ab 2.45 ± 0.10ab 2.60 ± 0.12a 2.40 ± 0.14ab
a

Data are presented as mean ± SEM, n = 6/group. Different letters on the shoulder mark indicate a significant difference (P < 0.05), the same letter or no letter indicates that the difference is not significant (P ≥ 0.05).

b

GSH-PX, glutathione peroxidase; SOD, superoxide dismutase; GSH, glutathione; GSSG, oxidized glutathione; MDA, malondialdehyde; T-AOC, total antioxidant capacity.

c

ANT, control diet + 300 mg/kg antibiotics; CON, control diet; HRC, control diet + curcumin and resveratrol (300 mg/kg); LRC, control diet + curcumin and resveratrol (100 mg/kg); RES, control diet + 300 mg/kg resveratrol; CUR, control diet + 300 mg/kg curcumin.