Table 1.
Spatial repositioning of target genes in prostate cancer.
| Tissue | SP100 | TGFB3 | SATB1 | LMNA | Gleason score | Gleason Grade | TNM | Risk |
|---|---|---|---|---|---|---|---|---|
| C1 | I | 9 (4 + 5) | 4 | T3N0M1 | High | |||
| C2 | 9 (5 + 4) | 4-5 | T2N1M1c | High | ||||
| C3 | I | 9 (5 + 4) | 5 | T3aN0M0 | High | |||
| C4 | I | 8 (4 + 4) | 4 | T3N0M0 | High | |||
| C5 | I | 9 (4 + 5) | T2N0M0 | High | ||||
| C6 | P | I | P | 9 (4 + 5) | T2N0M0 | High | ||
| C7 | I | 9 (4 + 5) | T2N0M0 | High | ||||
| C8 | P | P | 8 (4 + 4) | 4 | Unknown | High | ||
| C9 | 7 (3 + 4) | 4 | T3N0M1b | High | ||||
| C10 | 7 (3 + 4) | 3 | T4N1M1c | High | ||||
| C11 | I | I | 7 | 3 | T3N0 | High | ||
| C12 | 7 | 3 | T2N0 | Intermediate | ||||
| C13 | 7 | 3 | T2N0 | Intermediate | ||||
| C14 | I | P | 7 (3 + 4) | T2N0M0 | Intermediate | |||
| C15 | I | I | 7 (3 + 4) | 4 | T2N0M0 | Intermediate | ||
| C16 | I | 7 (3 + 4) | 4 | T2N0M0 | Intermediate | |||
| C17 | I | 7 (3 + 4) | T1N0M0 | Intermediate | ||||
| C18 | 7 | T2N0 | Intermediate | |||||
| C19 | 7 | T2N0 | Intermediate | |||||
| C20 | P | I | 4 (2 + 2) | 2 | T4N1M1 | High | ||
| C21 | P | P | 3 (1 + 2) | 2 | T3N1M1 | High | ||
| C22 | 6 (2 + 4) | 4 | T3N0M1b | High | ||||
| C23 | 6 (3 + 3) | 3 | T3N1M0 | High | ||||
| C24 | P | 6 (3 + 3) | 3 | T3N0M0 | High | |||
| C25 | P | P | 6 (3 + 3) | 3 | T2N0M0 | Low | ||
| C26 | P | P | I | 6 (3 + 3) | 3 | T2N0M0 | Low | |
| C27 | 6 | T2N0 | Low | |||||
| C28 | P | I | 5 (1 + 4) | T2N0M0 | Low | |||
| C29 | 5 (2 + 3) | 3 | T2N0M0 | Low | ||||
| C30 | 5 (2 + 3) | 3 | T2N0M0 | Low | ||||
| C31 | I | 4 (2 + 2) | 2 | T2N0M0 | Low | |||
| C32 | 3 (1 + 2) | 1 | T1N0M0 | Low |
Statistical comparisons of the RRD of a gene in individual cancer tissues to the PND, using the two-sample 1D KS test. Red, significantly different (P < 0.01); Blue, statistically similar position (P > 0.01). I, a more internal position in the cancer, compared to the PND; P, a more peripheral positioned in the cancer tissue; Red text: mark of aggressive/high risk cancer; blue text: mark of low risk cancer; purple text, intermediate Gleason score. Low risk, Gleason score 2-6 and T1/2 and N0M0; intermediate risk, Gleason score 7 and T1/2 and N0M0; high risk, Gleason score 8-10 and/or T3/4 and/or N1 and/or M1.