TABLE 3. Evolution of iron metabolism biochemical indicators at preoperative time and 1, 2, 3, 4, 5 and 10 years after Roux-en-Y gastric bypass.
Iron | LIBC | Ferritin | Hemoglobin | Hematocrit | |||||||||||
(ug/dl) | (ug/dl) | (ng/ml) | (g/dl) | (%) | |||||||||||
n | Mean±SD | (%) | n | Mean±SD | (%) | n | Mean±SD | (%) | n | Mean±SD | (%) | n | Mean±SD | (%) | |
Preoperative | 360 | 74.8±27.6 | 9.2 | 346 | 248.1±66.3 | 35.8 | 328 | 161.4±133.0 | 1.8 | 434 | 13.3±1.7 | 15.7 | 441 | 40.5±4.9 | 11.6 |
1 year PO | 337 | 84.3±35.3a | 8.9 | 243 | 218.5±79.3a | 31.1 | 315 | 134.4±133.6a | 3.5 | 336 | 12.9±1.9a | 28 | 335 | 39.5±4.2a | 16.7 |
2 years PO | 152 | 83.4±38.6a | 10.5 | 133 | 261.9±96.6b | 43.8 | 143 | 92.1±103.7a,b | 7 | 148 | 12.7±2a | 31.8 | 148 | 39.0±4.4a | 17.6 |
3 years PO | 137 | 75.2±35.3b,c | 17.5 | 122 | 273.1±97.3a,b | 43.8 | 129 | 76.2±104.9a,b | 14.7 | 139 | 12.3±2.3a,b | 34.5 | 139 | 37.6±5.5a,b,c | 24.5 |
4 years PO | 99 | 80.5±39.2 | 14.1 | 89 | 267.2±90.6b | 39.4 | 95 | 58.7±87.6a,b,c | 8.4 | 104 | 12.4±1.8a,b | 35.6 | 104 | 38.0±3.7a,b | 19.2 |
5 years PO | 65 | 72.6±33.4b,c | 18.5 | 68 | 275.2±91.4a,b | 50 | 60 | 40.0±53.5a,b,c | 13.3 | 70 | 12.4±1.4a,b | 38.6 | 70 | 37.4±5.5a,b,c | 20 |
10 years PO | 27 | 75.4±49.4a,e | 18.5 | 27 | 243.8±114.8d,e | 44.4 | 27 | 54.1±86.4a,b,c | 11.1 | 27 | 12.7±2.2a | 22.2 | 27 | 38.7±5.9a,b | 22.2 |
PO=postoperative time; n=number of patients evaluated; (%)=percentage of patients with values outside the normal range; LIBC=latent iron binding capacity; a=p<0.05 compared to preoperative; b=p<0.05 compared to one year PO; c=p<0.05 compared to two years PO; d=p<0.05 compared to three years PO; e=p<0.05 compared to five years PO