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. 2019 Oct 21;32(3):e1453. doi: 10.1590/0102-672020190001e1453

TABLE 4. Evolution of vitamin and protein metabolism biochemical indicators at preoperative time and 1, 2, 3, 4, 5 and 10 years of Roux-en-Y gastric bypass.

Albumin Total protein Vitamin B12 Folic acid
(g/dl) (g/dl) (Ng/ml) (Pg/ml)
n Mean±SD (%) n Mean±SD (%) n Mean±SD (%) n Mean±SD (%)
Preoperative 380 4.1±1.9 5.8 345 7.0±0.5 3.5 308 408.2±201.0 4.2 315 10.1±5.4 1.3
1 year PO 328 4.2±2.1 4.0 296 6.7±0.5a 3.7 294 346.4±202.6a 6.8 278 15.1±6.5a 0.7
2 years PO 152 4.1±0.3 2.6 148 6.8±0.4a 4.1 142 315.1±171.6a 12 143 14.9±6.7a 0
3 years PO 135 4.4±3.2 1.5 131 6.7±0.5a 3.8 122 332.2±189.0a 11.5 126 15.0±6.3a 0.8
4 years PO 100 4.1±0.2 2 94 6.7±0.5a 3.2 94 284.3±178.9a,b 20.2 90 15.8±6.8a 2.2
5 years PO 58 4.2±0.2 1.7 59 6.7±0.4a 1.7 62 310.4±186.0a 17.7 62 16.3±6.3a 0
10 years PO 27 4±0.4 3.7 27 6.5±0.7a 11.1 27 379.8±255.6 11.1 27 18.3±6.5 a 3.7

PO=postoperative time; n=number of patients evaluated; (%)=percentage of patients with values outside the normal range; a=p<0.05 compared to preoperative; b=p<0.05 compared to one year PO; c=p<0.05 compared to two years PO