Table 1.

Iterations of Failure-Free Days in Emergency and Critical Care Trials

Outcome	Time Frame (d)	Primary or Secondary Outcome	References
Ventilator-free days	28	Primary	4, 6, 42, 43
	60	Primary	44
	180	Secondary	7
Vasopressor-free days	28	Secondary	45, 46, 47
Kidney failure–free days	28	Primary	48
Renal replacement therapy–free days	28	Secondary	46, 47, 49
Delirium-/coma-free days	14	Primary	50
Organ failure–free days	14	Secondary	51
	28	Secondary	4, 6, 45, 47
ICU-free days	7	Secondary	22
	28	Primary	52
	180	Secondary	7
Hospital-free days	28	Primary	53