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. 2019 Sep 27;18(5):3959–3967. doi: 10.3892/etm.2019.8063

Figure 5.

Figure 5.

Effects of HOTAIR and miR-211 overexpression or knockdown on the mRNA expression of various inflammatory factors, miR-211 and HOTAIR. The relative level of (A) IFN-γ, IL-6, IL-17, TNF-α, IL-1β, and IL-6R and (B) miR-211, and HOTAIR expression in monocytes transfected with HOTAIR, miR-211 mimics, and miR-211 inhibitor was examined using reverse transcription-quantitative PCR. *P<0.05, **P<0.01 vs. control group; #P<0.05, ##P<0.01 vs. NC group. Each experiment was repeated three times. HOTAIR, hox transcript antisense RNA; miR, microRNA; IL, interleukin; TNF, tumor necrosis factor; IFN, interferon; lncRNA, long non-coding RNA; NC, negative control for miRNA mimic and inhibitor; Control, empty vector that do not express HOTAIR.