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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: J Biomed Mater Res B Appl Biomater. 2019 Apr 23;108(2):306–315. doi: 10.1002/jbm.b.34389

TABLE 2.

Median Inflammation Scores (Minimum and Maximum) at 3 and 30 Days.

SHAM PDS 1MET 2MET 1CIP 2CIP

3 days 1 (0–1) 1 (1–2) 1 (0–2) 1.5 (0–2) 1 (1–2) 1 (1–2)
30 days 0 (0–1) 0 (0–1) 0 (0–2) 1 (0–2) 1 (0–1) 1 (0–2)

Score system from verbal description using a 4-point scale considering polymorphonuclear leukocytes/mononuclear cells: 0=absent (no inflammatory cells); 1=mild or discrete (few inflammatory cells); 2=moderate (several inflammatory cells and increased reaction zone); and 3=intense or severe (increased reaction zone, occasional foci of neutrophil granulocytes and/or lymphocytes). Sections were viewed at 100× and graded by a blinded and calibrated examiner. Five animals per group and time point were used.