TABLE 2.
SHAM | PDS | 1MET | 2MET | 1CIP | 2CIP | |
---|---|---|---|---|---|---|
3 days | 1 (0–1) | 1 (1–2) | 1 (0–2) | 1.5 (0–2) | 1 (1–2) | 1 (1–2) |
30 days | 0 (0–1) | 0 (0–1) | 0 (0–2) | 1 (0–2) | 1 (0–1) | 1 (0–2) |
Score system from verbal description using a 4-point scale considering polymorphonuclear leukocytes/mononuclear cells: 0=absent (no inflammatory cells); 1=mild or discrete (few inflammatory cells); 2=moderate (several inflammatory cells and increased reaction zone); and 3=intense or severe (increased reaction zone, occasional foci of neutrophil granulocytes and/or lymphocytes). Sections were viewed at 100× and graded by a blinded and calibrated examiner. Five animals per group and time point were used.