Table 1.
Baseline Characteristics, Plasma Lipid Levels and WMH Volume (N=588)
| Characteristics | Median (IQR)/N(%) |
|---|---|
| General Information | |
| Age | 68.0 (64.2, 71.9) |
| Male | 302 (51.4%) |
| Hypertension | 335 (57.0%) |
| WMH volume (% TIV) | 0.005 (0.003, 0.010) |
| Plasma lipid levels, ng/ml | |
| Sphingosine-1-phosphate | 223.1 (185.8, 265.1) |
| Ceramides, ng/ml | |
| C14:0 | 9.0 (6.8, 12.5) |
| C16:0 | 88.8 (74.3, 105.3) |
| C18:0 | 78.1 (59.4, 98.3) |
| C18:1 | 2.3 (1.4, 3.6) |
| C20:0 | 226.1 (190.7, 274.9) |
| C22:0 | 701.9 (574.1, 859.8) |
| C23:0 | 418.7 (344.0, 505.9) |
| C24:0 | 1214.8 (993.8, 1461.8) |
| C24:1 | 314.8 (257.1, 376.0) |
| Ceramide ratios | |
| C16:0_24:0 | 0.07 (0.06, 0.09) |
| C18:0_24:0 | 0.06 (0.05, 0.08) |
| C24:1_24:0 | 0.26 (0.21, 0.32) |
| Ceramide score | 4.0 (2.0, 7.0) |
IQR, Interquartile range; WMH, white matter hyperintensity; TIV, Total intracranial volume. WMH is expressed as the percent of the total intracranial volume.