Skip to main content
. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Ann Epidemiol. 2019 Aug 22;38:35–41. doi: 10.1016/j.annepidem.2019.08.005

Table 3.

Propensity score weighted, adjusted HR for periodontitis and total cancer incidence or deaths and for colorectal and lung cancer incidence

All Cancer Incidence Cases Person-years HR* 95% CI p All Cancer Death Cases Person-years HR* 95% CI p
Periodontitis (CDC-AAP) Periodontitis (CDC-AAP)
 No 331 22857 1  No 85 24910 1
 Mild 118 9734 1.28 0.77 2.12 0.345  Mild 32 10442 1.71 0.83 3.51 0.146
 Moderate 560 32491 1.02 0.88 1.19 0.772  Moderate 180 35565 1.22 0.94 1.61 0.149
 Severe 292 14066 1.09 0.92 1.30 0.331  Severe 101 15475 1.39 1.02 1.89 0.037
 Ptrend 0.617  Ptrend 0.104
Edentulism 347 16447 1.17 0.97 1.40 0.095 Edentulism 149 17996 1.62 1.19 2.22 0.002
Periodontitis (ARIC) Periodontitis (ARIC)
 No/mild 451 34437 1  No/mild 117 37195 1
Moderate 467 27392 1.21 1.05 1.39 0.011 Moderate 138 30098 1.20 0.93 1.57 0.167
Severe 383 17319 1.23 1.05 1.44 0.009 Severe 143 19099 1.49 1.14 1.95 0.004
Ptrend 0.006 Ptrend 0.004
Edentulism 347 16447 1.30 1.11 1.54 0.003 Edentulism 149 17996 1.72 1.31 2.27 0.0002
Colorectal Cancer Incidence Cases Person-years HR* 95 % CI p Lung Cancer Incidence Cases Person-years HR* 95% CI p
Periodontitis (CDC-AAP) Periodontitis (CDC-AAP)
 No 30 22857 1  No 21 22857 1
 Mild 7 9734 3.46 1.39 8.62 0.0077  Mild 16 9734 2.04 0.88 4.71 0.097
 Moderate 46 32491 1.12 0.68 1.84 0.652  Moderate 62 32491 1.39 0.81 2.38 0.234
Severe 33 14066 1.77 1.03 3.05 0.039 Severe 53 14066 2.51 1.45 4.33 0.001
Ptrend 0.395 Ptrend 0.004
Edentulism 46 16447 1.59 0.94 2.70 0.085 Edentulism 74 16447 2.92 1.67 5.10 0.0002
Periodontitis (ARIC) Periodontitis (ARIC)
 No/mild 42 34437 1  No/mild 34 34437 1
 Moderate 33 27392 1.13 0.64 1.98 0.677  Moderate 48 27392 1.22 0.74 1.99 0.435
 Severe 41 17319 1.42 0.87 2.32 0.157  Severe 70 17319 2.17 1.39 3.40 0.0007
 Ptrend 0.169  Ptrend 0.0006
Edentulism 46 16447 2.04 1.22 3.41 0.007 Edentulism 74 16447 2.83 1.75 4.59 0.0008
*

All Cox models are adjusted for age, field center by race, education level, smoking status, smoking duration, drinking status, body mass index, diabetes status (diagnosed diabetes, undiagnosed diabetes, at risk for diabetes [reference is normal]), joint terms for sex and HRT use (female nonuser, female user [reference is men]), and edentulism status. The propensity score was generated based on lifecourse SES neighborhood income, health insurance status, frequency of routine physical examination, having a dentist, frequency of routine dental visit, last time of dental visit. The inverse of the propensity score was used as a weight in the Cox model. Confidence interval was generated based on robust sandwich variance.