A. Concentration-dependent changes of p-Ser15 P53, P21Cip1, GADD45, CyclinB, P27Kip1, and p-Thr68 Chk2, and anti-apoptotic proteins Bcl-xL and survivin in PANC-1 cells treated with MSeA for 24 h. B. Time course of MSeA-induced changes of Cyclin B, Cdc2/Cdk1, p-Ser473 AKT and survivin in PANC-1 cells. β-Actin served as loading control.