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. 2019 Jun 20;4(3):135–140. doi: 10.1136/svn-2018-000202

Table 2.

Domain-specific cognitive z-scores in no atrophy, CA and CA+MTA groups in different CeVD groups

Groups
Cognitive scores None-mild CeVD Moderate-severe CeVD P
(for trend)
No atrophy (n=362) CA (n=133) CA+MTA (n=25) No atrophy (n=109) CA (n=132) CA+MTA (n=58)
Executive function 0.27
(0.18, 0.36)		 0.23
(0.10, 0.37)		 −0.21
(−0.53,0.11)		 0.19
(0.03, 0.34)*		 0.07
(−0.10, 0.23)†		 −0.33
(−0.64,–0.02)*†		 0.002
Attention 0.28
(0.19, 0.36)		 0.22
(0.08, 0.36)		 −0.04
(−0.37, 0.28)		 0.16
(0.01, 0.32)		 −0.20
(−0.37,–0.03)		 −0.35
(−0.66,–0.04)		 0.001
Language 0.28
(0.19, 0.36)		 0.22
(0.08, 0.36)		 −0.04
(−0.37, 0.28)		 0.16
(0.01, 0.32)		 −0.20
(−0.37,–0.04)		 −0.35
(−0.66,–0.04)		 <0.001
Verbal memory 0.35
(0.26, 0.44)		 0.23
(0.09, 0.38)		 −0.19
(−0.52, 0.14)		 0.08
(−0.08, 0.24)		 0.01
(−0.16, 0.18)		 −0.25
(−0.56,0.07)		 <0.001
Visual memory 0.33
(0.25, 0.41)		 0.27
(0.14, 0.40)		 −0.23
(−0.53, 0.07)		 0.19
(0.04, 0.33)*		 −0.12
(−0.27, 0.03)		 −0.39
(−0.67,–0.11)*		 <0.001
Visuoconstruction 0.30
(0.21, 0.38)		 0.24
(0.10, 0.38)		 −0.30
(−0.63, 0.02)		 0.09
(−0.06, 0.25)		 0.04
(−0.12, 0.21)		 −0.09
(−0.39, 0.22)		 0.002
Visuomotor speed 0.31
(0.23, 0.39)		 0.18
(0.05, 0.30)		 −0.29
(−0.57, 0.003)		 0.11
(−0.03, 0.24)*		 0.09
(−0.05, 0.24)†		 −0.22
(−0.49, 0.06)†		 <0.001

Values are adjusted means (95% CI). CeVD, Cerebrovascular Disease. The model controlled for age, education, gender and cognitive impairment status.

*Significant difference between no atrophy and CA+MTA groups.

†Significant difference between CA and CA+MTA groups.