Table 4. Animal characteristics of Ovx animals treated with 17beta-estradiol (E2) at the end of the protocol.
Parameters | ShOvx + E2 (n = 6) | AROvx + E2 (n = 8) | p-value |
---|---|---|---|
Body weight, g | 342 ± 8 | 320 ± 11 | 0.096 |
Tibial length, mm | 48 ± 0.3 | 48 ± 0.3 | 0.69 |
Heart, mg | 870 ± 26 | 1,223 ± 39 | <0.0001 |
Heart/BW, mg/g | 2.5 ± 0.07 | 3.9 ± 0.10 | <0.0001 |
Heart/TL, mg/mm | 18.0 ± 0.5 | 25.6 ± 0.7 | <0.0001 |
Left ventricle, mg | 650 ± 20 | 973 ± 24 | <0.0001 |
Left atria, mg | 21 ± 1 | 34 ± 3 | <0.0001 |
Lungs, mg | 1.5 ± 0.1 | 1.6 ± 0.1 | 0.89 |
Uterus, mg | 37 ± 2.3 | 40 ± 3.1 | 0.55 |