Table 2.

Neuroscore of rats in the MRI and EEG groups at the different sites.

MRI	Site	Baseline	2 d	7 d	14 d	21 d	28 d
		Mean (range, n)	Mean (range, n)	Mean (range, n)	Mean (range, n)	Mean (range, n)	Mean (range, n)
Sham	1	28 (28 – 26, n = 13)^¤¤¤	27 (28 – 25, n = 13)^¤¤¤	27 (28 – 25, n = 13) ^¤¤¤	28 (28 – 25, n = 13) ^¤¤¤	27 (28 – 26, n = 13) ^¤¤¤	27 (28 – 26, n = 13) ^¤¤¤
	2	28 (28 – 28, n = 9)	28 (28 – 27, n = 10)	28 (28 – 22, n = 9)	28 (28 – 24, n = 8)	28 (28 – 20, n = 10)	27 (28 – 24, n = 8)
	3	26 (28 – 24, n = 9)^*⁺	25 (28 – 21, n = 9)	23 (27 – 21, n = 9)^**	25 (27 – 22, n = 9)^**	25 (26 – 24, n = 9)^*	24 (26 – 24, n = 8)^**
TBI	1	28 (28 – 28, n = 45) ^¤¤¤	11 (21 – 1,11= 45)^¤¤¤	16 (24 – 8, n = 45) ^¤¤¤	17 (24 – 10, n = 45) ^¤¤¤	18 (26 – 12, n = 45) ^¤¤¤	20 (28 – 11, n = 45) ^¤¤¤
	2	28 (28 – 28, n = 18)^***	17 (22 – 6, n = 20)^***	21 (27 – 17, n = 19)^***	20 (27 – 16, n = 13)^***	25 (28 – 17, n = 20)^***	25 (28 – 20, n = 15)^***
	3	27 (28 – 24, n = 14)	13 (17 – 10, n = 14)⁺	21 (25 – 17, n = 14)^***	25 (26 – 22, n = 14)^***	24 (26 – 22, n = 14)^***	25 (27 – 23, n = 11)^***
EEG
Sham	2	28 (28 – 28, n = 3)	23 (23 – 20, n = 3)	27 (28 – 26, n = 3)	26 (27 – 25, n = 3)	27 (27 – 27, n = 2)	26 (28 – 26, n = 3)
	3	26 (26 – 25, n = 7)	24 (26 – 22, n = 7)	24 (26 – 23, n = 7)⁺	24 (26 – 20, n = 7)	23 (25 – 21, n = 7)⁺⁺	23 (24 – 22, n = 7)⁺⁺⁺
TBI	2	28 (28 – 28, n = 10)	12 (16 – 7, n = 8)	17 (20 – 13, n = 8)	17 (22 – 15, n = 8)	19 (24 – 16, n = 6)	22 (26 – 21, n = 7)
	3	27 (28 – 25, n = 13)	11 (15 – 9, n = 13)	19 (21 – 17, n = 13)	24 (28 – 22, n = 9)⁺	25 (27 – 22, n = 9)⁺	23 (26 – 21, n = 9)

Site 1, University of Eastern Finland (UEF); Site 2, University of Monash (Melbourne); Site 3, University California (UCLA). Abbreviation: d, day; EEG, electroencephalography; n, number of animals; TBI, traumatic brain injury. Statistical significances:

^¤¤¤

p < 0.001, comparison between all sites (Kruskal-Wallis test);

p < 0.05,

^**

p < 0.01,

^***

p < 0.001 comparison with UEF (Dunn’s multiple comparison and Mann-Whitney U test);

⁺

p < 0.05,

⁺⁺

p < 0.01,

⁺⁺⁺

p < 0.001, comparison between Melbourne (Dunn’s multiple comparison and Mann-Whitney U test).