Skip to main content
. 2019 Oct 24;14(10):e0223889. doi: 10.1371/journal.pone.0223889

Fig 5. Spleen PAX5 significantly decreased in APRIL/BLyS blockade treated mice.

Fig 5

Preservation of splenic germinal center seen in (A) syngeneic transplant control and (B) untreated transplant group. B lymphocytes are shown in brown; T lymphocytes are shown in blue. (C) Destruction of normal germinal center seen in animals treated with APRIL/BLyS blockade as indicated black outline. (D) Densitometry using anti-PAX5 antibody to detect B lymphocytes in splenic germinal centers. Graph depicts percentage of total area of spleen staining for anti-PAX5.