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. 2019 Oct 24;14(10):e0224064. doi: 10.1371/journal.pone.0224064

Table 4. Comparison of hazard ratio estimates for breast cancer survival in months 1–24 and 25–60 post diagnosis.

Relationships that failed to meet the proportional hazards assumption denoted in bold and by **. All others (non-bold) provided for completeness.

Diagnosis Years 1–24 mo post diagnosis 25–60 mo post diagnosis
Hazard ratio 95% CI^ Hazard ratio 95% CI^
1990–1994:
    White Non-Hispanic 1.0 1.0
    Hispanic** 1.42 (1.22–1.57) 1.30 (1.18–1.44)
    Black 2.36 (2.21–2.52) 1.90 (1.78–2.04)
    American Indian/
    Alaskan Native
1.14 (0.79–1.65) 1.29 (0.95–1.77)
1995–1999:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.57 (1.42–1.72) 1.48 (1.36–1.62)
    Black** 2.36 (2.22–2.51) 1.90 (1.78–2.03)
    American Indian/
    Alaskan Native
1.57 (1.19–2.08) 1.71 (1.33–2.20)
2000–2004:
    White Non-Hispanic 1.0 1.0
    Hispanic** 1.51 (1.42–1.61) 1.38 (1.30–1.47)
    Black 2.51 (2.41–2.62) 1.97 (1.89–2.06)
    American Indian/
    Alaskan Native**
1.10 (0.84–1.44) 1.57 (1.28–1.93)
2005–2009:
    White Non-Hispanic 1.0 1.0
    Hispanic** 1.33 (1.25–1.41) 1.30 (1.23–1.38)
    Black 2.25 (2.16–2.35) 1.89 (1.80–1.97)
    American Indian/
    Alaskan Native**
1.49 (1.20–1.85) 1.52 (1.24–1.85)
Estrogen receptor positive:
Diagnosis Years 1–24 mo post diagnosis 25–60 mo post diagnosis
Hazard ratio 95% CI^ Hazard ratio 95% CI^
1990–1994:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.39 (1.14–1.69) 1.25 (1.07–1.47)
    Black 2.34 (2.05–2.67) 1.83 (1.63–2.05)
    American Indian/
    Alaskan Native
1.26 (0.66–2.42) 1.54 (0.98–2.42)
1995–1999:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.34 (1.10–1.63) 1.48 (1.28–1.69)
    Black** 2.56 (2.26–2.89) 1.92 (1.73–2.14)
    American Indian/
    Alaskan Native
1.81 (1.09–3.00) 1.70 (1.16–2.49)
2000–2004:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.37 (1.21–1.54) 1.37 (1.25–1.50)
    Black** 2.49 (2.30–2.69) 1.92 (1.79–2.06)
    American Indian/**
Alaskan Native
1.06 (0.66–1.71) 1.63 (1.22–2.18)
2005–2009:
    White Non-Hispanic 1.0 1.0
    Hispanic** 1.20 (1.08–1.32) 1.28 (1.18–1.39)
    Black 2.10 (1.96–2.25) 1.97 (1.86–2.10)
    American Indian/
    Alaskan Native
1.74 (1.27–2.37) 1.51 (1.15–1.96)
Estrogen receptor negative:
Diagnosis Years 1–24 mo post diagnosis 25–60 mo post diagnosis
Hazard ratio 95% CI^ Hazard ratio 95% CI^
1990–1994:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.14 (0.94–1.38) 1.11 (0.91–1.34)
    Black 1.63 (1.45–1.84) 1.51 (1.34–1.71)
    American Indian/
    Alaskan Native
1.09 (0.59–2.04) 1.28 (0.73–2.26)
1995–1999:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.29 (1.11–1.51) 1.37 (1.16–1.61)
    Black 1.57 (1.42–1.75) 1.50 (1.34–1.69)
    American Indian/
    Alaskan Native
1.59 (1.07–2.36) 1.83 (1.22–2.74)
2000–2004:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.25 (1.13–1.39) 1.23 (1.10–1.36)
    Black** 1.74 (1.63–1.86) 1.45 (1.35–1.56)
    American Indian/
    Alaskan Native**
0.85 (0.54–1.31) 1.60 (1.14–2.24)
2005–2009:
    White Non-Hispanic 1.0 1.0
    Hispanic 1.17 (1.07–1.29) 1.12 (1.01–1.24)
    Black** 1.67 (1.57–1.78) 1.35 (1.25–1.45)
    American Indian/
    Alaskan Native
1.33 (0.95–1.86) 1.48 (1.04–2.09)

Abbreviations: ^ CI–confidence interval

** Proportional hazards assumption violated

Note: Proportional hazards assumption violated only in 1990–1994 diagnoses or later.