Table 2. Tissue specific localization of ESR1, ESR2 and PGR in mouse uterus that were treated with DEHP or NP. Quantification is presented by the number of + or −, negative.
| μg/L | ESR1 | ESR2 | PGR | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| St | GE | LE | St | GE | LE | St | GE | LE | ||
| Contl | Nucleus | +++ | +++ | +++ | ++ | − | ++ | ++ | − | − |
| Cytoplasm | − | − | − | − | +++ | +++ | ++ | +++ | +++ | |
| DEHP 133 | Nucleus | +++ | +++ | +++ | ++ | ++ | ++ | +++ | +++ | +++ |
| Cytoplasm | − | +++ | +++ | − | +++ | +++ | − | +++ | +++ | |
| DEHP 1330 | Nucleus | + | − | − | + | − | − | + | − | − |
| Cytoplasm | − | +++ | +++ | − | +++ | +++ | − | +++ | +++ | |
| NP 50 | Nucleus | +++ | − | − | +++ | − | − | +++ | +++ | +++ |
| Cytoplasm | − | +++ | +++ | − | +++ | +++ | − | +++ | +++ | |
| NP 500 | Nucleus | +++ | − | − | +++ | − | − | + | − | − |
| Cytoplasm | − | +++ | +++ | − | +++ | +++ | − | +++ | +++ | |
St, stroma; GE, glandular epithelium; LE, luminal epithelium; Cont, control.
ESR1, estrogen receptor 1; ESR2, estrogen receptor 2; PGR, progesterone receptor; DEHP, di(2 ethylhexyl) phthalate; NP, nonylphenol.