Fig. 9.

Mice MDA-MB-231 tumors overexpressing lncE/BC200, and histological sectioning. a Tumors dissected from each mice at end of 4 weeks. b Representative H&E stained section of poorly differentiated tumor at end point (4 weeks) (40x magnification). c Tumor weight at end point. ***p.value < 0.001. lncE: lncEPCAM. a shows the dissected tumors at end point for MDA-MB-231. H&E staining of poorly differentiated adenocarcinoma is shown in b. As c shows, mice containing MDA-MB-231-lncEPCAM cells in the mammary fat pad, grow significantly larger tumors compared to MDA-MB-231-GFP in the 4-week period of the experiment