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. 2019 Oct 23;12:499. doi: 10.1186/s13071-019-3749-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — High-transmission setting: prevalence (left) and heavy intensity infection prevalence (right) in SAC and adults during 30 years of control. Shaded regions represent the 95% prediction interval (i.e. 95% of all stochastic simulations lie within this region). a MDA targeted at SAC with 75% coverage. b Cohort vaccination (at 1- and 10 years-old). c Cohort vaccination (at 1- and 10 years-old) and a catch-up campaign in the first year. d Mass SAC vaccination, every 5 years. In all cases the vaccine is assumed to offer 10 years protection