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. 2019 Oct 23;13:78. doi: 10.1186/s13036-019-0206-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Influence of dissolved oxygen on H7N9-TW VLP production. High Five™ cells were cultured in 500-mL spinner flasks, spinner flasks, and

shake flasks with air ventilation (100 mL/min) and infected with baculovirus. The DO concentration profile (a) and H7N9-TW VLP production profile (b) were monitored during the upstream process