Table 2.

Module 2 GO and KEGG pathways analysis.

	ID	GO-term	Count	p-value
Biological process	GO:0050896	Response to stimulus	214	1.08E-23
	GO:0065008	Regulation of biological quality	127	2.60E-18
	GO:0010033	Response to organic substance	110	5.34E-18
	GO:0042221	Response to chemical	137	1.32E-17
	GO:0043062	Extracellular structure organization	38	1.58E-17
Molecular function	GO:0005488	Binding	242	1.86E-10
	GO:0005102	Signaling receptor binding	64	1.86E-10
	GO:0030545	Receptor regulator activity	33	8.42E-10
	GO:0004252	Serine-type endopeptidase activity	21	8.42E-10
	GO:0048018	Receptor ligand activity	31	3.00E-09
Cellular component	GO:0044421	Extracellular region part	92	1.22E-30
	GO:0005576	Extracellular region	123	1.22E-30
	GO:0005615	Extracellular space	76	5.72E-25
	GO:0031012	Extracellular matrix	30	1.14E-13
	GO:0044420	Extracellular matrix component	14	4.21E-10
	Pathways	Description
KEGG pathways	hsa04080	Neuroactive ligand-receptor interaction	23	3.49E-08
	hsa04657	IL-17 signaling pathway	12	6.60E-06
	hsa04512	ECM-receptor interaction	11	9.63E-06
	hsa00830	Retinol metabolism	10	9.63E-06
	hsa04610	Complement and coagulation cascades	10	3.33E-05